Lipid-Sirt® provides support for vascular integrity and healthy aging by supporting and stimulating sirtuin activity. Specific nutritional compounds have been demonstrated to have a positive impact on cholesterol levels. Lipid-Sirt® supplies some of these specific nutrients, which have been demonstrated to: 1) modify the production of cholesterol in the liver by reacting with hepatic enzymes, 2) increase cholesterol excretion via the bile, 3) inhibit cholesterol uptake from the intestine, and 4) support increased levels of HDL.